Despina Panayiotou Theodossiou was Chief Executive Officer, and later co-CEO, of Tototheo Maritime. She was President of WISTA Cyprus and later President of WISTA International, to which she was re-elected.
She gave a keynote address at Mare Forum's 5th Mare Forum Cyprus in 2016 and spoke as a panellist at the 2nd Mare Forum Mykonos in 2018.